Document Type : Original Article


1 Ph.D. Candidate, Department Of Psychology, Islamic Azad University, Tehran, Iran

2 Department of Psychology, Faculty of Psychology, Islamic Azad University, Roudhen Branch, Iran

3 Department of MD-Child Psychiatrist, Baqiayatallah University of Medical Sciences, Tehran, Iran


This study aimed at determining the effect of forehead cortex electric current stimulation on inhibitory control and working memory in people with attention deficit and hyperactivity disorder (ADHD), using TDCS device. The method used was quasi-experimental research with pretest-posttest control group design. The participants were 24 children with attention deficit and hyperactivity disorder aged 7-11 who referred to Baqiyatallah Hospital in 1397. Children were randomly divided into experimental (n = 12) and control (n = 12) groups. The experimental group was intervened in 10 sessions, 3 times a week, and each session was 20 minutes. Assessments were performed in 3 steps, a day before the intervention, and a day after the intervention ended, and finally at the follow-up phase, two months after the intervention was accomplished. Go/no Go and N-back tests were used to evaluate inhibitory control and working memory, respectively.  A repeated measurement method was applied to analyze the data. Findings revealed that brain electric stimulation program improves working memory and inhibitory control in children with attention deficit hyperactivity disorder. Therefore, brain electric stimulation program can be used to enhance the working memory and inhibitory control of children with attention deficit hyperactivity disorder.


  1. Alipor, A., Khozaymeh, M., & Zareh, H. (2013). Comparing time perception by various durations in children with and without ADHD. JOEC, 13(1), 5-14.
  2. American Psychiatric Association. (2000). Diagnostic criteria from dsm-iv-tr. American Psychiatric Pub.
  3. Arkan, A., & Yaryari, F. (2014). Effect of transcranial direct current stimulation (TDCS) on working memory in healthy people. JCP, 2(2), 10-17.
  4. Bickel, W. K., Yi, R., Landes, R. D., Hill, P. F., & Baxter, C. (2011). Remember the future: Working memory training decreases delay discounting among stimulant addicts. Biological Psychiatry69(3), 260-265.
  5. Biederman, J., Spencer, T., & Wilens, T. (2004). Evidence-based pharmacotherapy for attention-deficit hyperactivity disorder. International Journal of Neuropsychopharmacology, 7(1), 77-97.
  6. Bobova, L., Finn, P. R., Rickert, M. E., & Lucas, J. (2009). Disinhibitory psychopathology and delay discounting in alcohol dependence: Personality and cognitive correlates. Experimental and Clinical Psychopharmacology, 17(1), 51-61.
  7. Boggio, P. S., Ferrucci, R., Rigonatti, S. P., Covre, P., Nitsche, M., Pascual-Leone, A., & Fregni, F. (2006). Effects of transcranial direct current stimulation on working memory in patients with Parkinson's disease. Journal of the Neurological Sciences249(1), 31-38.
  8. Brunoni, A. R., Nitsche, M. A., Bolognini, N., Bikson, M., Wagner, T., Merabet, L., & Ferrucci, R. (2012). Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions. Brain Stimulation5(3), 175-195.
  9. Castellanos, F. X. (1997). Toward a pathophysiology of attention-deficit/hyperactivint disorder. Clinical Pediatrics36(7), 381-393.
  10. DaSilva, A. F., Volz, M. S., Bikson, M., & Fregni, F. (2011). Electrode positioning and montage in transcranial direct current stimulation. JoVE (Journal of Visualized Experiments), (51), e27-44.
  11. Capone, F., Capone, G., Ranieri, F., Di Pino, G., Oricchio, G., & Di Lazzaro, V. (2014). The effect of practice on random number generation task: a transcranial direct current stimulation study. Neurobiology of Learning and Memory114, 51-57.
  12. Gladwin, T. E., Den Uyl, T. E., Fregni, F. F., & Wiers, R. W. (2012). Enhancement of selective attention by tDCS: interaction with interference in a Sternberg task. Neuroscience Letters512(1), 33-37.
  13. Heckel, L., Clarke, A., Barry, R., McCarthy, R., & Selikowitz, M. (2009). The relationship between divorce and the psychological well‐being of children with ADHD: differences in age, gender, and subtype. Emotional and Behavioral Difficulties, 14(1), 49-68.
  14. Hinshaw, S. P. (2006). Treatment for children and adolescents with Attention-deficit/hyperactivity disorder. In P. C. Kendall (Ed.), Child and adolescent therapy: Cognitive-behavioral procedures, Third Edition. New York: Guilford Press
  15. Kane, M. J., Conway, A. R., Miura, T. K., & Colflesh, G. J. (2007). Working memory, attention control, and the N-back task: a question of construct validity. Journal of Experimental Psychology: Learning, Memory, and Cognition33(3), 615-622.
  16. Najarzadegan, M., Nejati, V., Amiri, N., & Sharifian, M. (2015). The effect of cognitive rehabilitation on executive functions (attention and working memory) in children with attention deficit / hyperactivity disorder. The Scientific Journal of Rehabilitation Medicine (SJRM), 4(2), 97-108.
  17. Najian, A., & Najati, V. (2017). Effectiveness of motor based cognitive rehabilitation on improvement of sustained attention and cognitive flexibility of children with ADHD. The Scientific Journal of Rehabilitation Medicine (SJRM), 6(4), 1-12.
  18. Nejati, V. (2013). Prevalence of behavioral problems in elementary school students in Tehran province. Journal of the Medical Council of the Islamic Republic of Iran, 30(2), 162-167.
  19. Nejati, Z., & Shirani, I. (2013). Neurological evidence of impairment of control and high risk decision making in smokers. Journal of Research in Behavioral Sciences, 11(1), 1-9.
  20. Nigg, J. T., Willcutt, E. G., Doyle, A. E., & Sonuga-Barke, E. J. (2005). Causal heterogeneity in attention-deficit/hyperactivity disorder: do we need neuropsychologically impaired subtypes? Biological Psychiatry57(11), 1224-1230.
  21. Pecchinenda, A., Ferlazzo, F., & Lavidor, M. (2015). Modulation of selective attention by polarity-specific tDCS effects. Neuropsychologia68, 1-7.
  22. Pelham Jr, W. E., & Fabiano, G. A. (2008). Evidence-based psychosocial treatments for attention-deficit/hyperactivity disorder. Journal of Clinical Child & Adolescent Psychology37(1), 184-214.
  23. Pennington, B. F. (2008). Diagnosing learning disorders: A neuropsychological framework. Guilford Press.
  24. Perfetti, B., Saggino, A., Ferretti, A., Caulo, M., Romani, G. L., & Onofrj, M. (2009). Differential patterns of cortical activation as a function of fluid reasoning complexity. Human Brain Mapping30(2), 497-510.
  25. Richa, S., Rohayem, J., Chammai, R., Kazour, F., Haddad, R., Hleis, S., & Gerbaka, B. (2014). ADHD prevalence in Lebanese school-age population. Journal of Attention Disorders18(3), 242-246.
  26. Roe, J. M., Nesheim, M., Mathiesen, N. C., Moberget, T., Alnæs, D., & Sneve, M. H. (2016). The effects of tDCS upon sustained visual attention are dependent on cognitive load. Neuropsychologia, 80, 1-8.
  27. Sakai, H., Uchiyama, Y., Tanaka, S., Sugawara, S. K., & Sadato, N. (2014). Prefrontal transcranial direct current stimulation improves fundamental vehicle control abilities. Behavioural brain research273, 57-62.
  28. Salehi, B., Moradi, S., Ebrahimi, S., & Rafeei, M. (2011). Comparison of ADHD (Attention Deficit Hyperactivity Disorder) prevalence between female and male students of primary schools in Arak City in academic year of 2009-2010. Scientific Journal of Kurdistan University of Medical Sciences16(2), 45-54.
  29. Zelazo, P. D., & Müller, U. (2002). Executive function in typical and atypical development. Blackwell Handbook of Childhood Cognitive Development, 445-469.
  30. Zoefel, B., Huster, R. J., & Herrmann, C. S. (2011). Neurofeedback training of the upper alpha frequency band in EEG improves cognitive performance. Neuroimage54(2), 1427-1431.